Dott. Prof. Valerio Sanguigni -Cardiologist

- Born in Rome on March 20, 1959

- Graduated top of his class from the Università degli Studi di Roma “La Sapienza” [La Sapienza University of Rome] with a Degree in Medicine and Surgery (July 1983)

- Became a member of the Ordine Provinciale di Roma dei Medici Chirurghi e degli Odontoiatri [Rome Provincial Board of Physicians, Surgeons, and Dentists] on January 12, 1984 under number: M 34080

- Received a Post-Graduate Degree in Cardiology, graduating top of his class from the Università degli Studi di Roma “La Sapienza” (July 1987)

- University Fellow, winner of the competition based on qualifications and exams in the Department of Internal Medicine, Division of Medical Pathology of the Università degli Studi di Roma “Tor Vergata” (April 1989)

- Adjunct Professor in the Faculty of Medicine of the Università Tor Vergata, appointed by the Chancellor (May 2005)

- Chief Physician in the University Division of Medical Pathology and then Internal Medicine of the Complesso Integrato Columbus [Columbus Integrated Complex], a hospital facility affiliated with the Università Tor Vergata di Roma, where he performed clinical activities as the doctor personally responsible for hospitalizations and department in-patient care and, in particular, organized and directed the Outpatient Cardiovascular Disease Clinic

- Currently he is the Director of the Internal Medicine and Endocrinology Unit of the Casa di Cura Madonna delle Grazie di Velletri [nursing home], which has a contract with the Italian National Health Service, where he also directs the Center for the Diagnosis and Treatment of Hypertension and the Antithrombosis Center

- Italian expert for the EMA (European Medicines Agency) appointed by the AIFA (Italian Medicines Agency) (October 2008)

- In December 2009, he was awarded the Honor of Knight of the Italian Republic by the President of the Republic

- In December 2013, he was awarded the Honor of Officer of the Republic by the President of the Republic

- In November 2018 it was granted to him the VISA O-1 for Extraordinaty Ability from the Department of Immigration of USA 

He is an ordinary member of the following Scientific Societies:

Società Italiana di Cardiologia [Italian Society of Cardiology]

Società Italiana di Medicina Interna [Italian Society of Internal Medicine]

Fellow of the American College of Angiology

Fellow of the European Society of Cardiology

Premium member of the American Heart Association


- Scientific reviewer of research projects and publications for ANVUR (Agenzia di Valutazione del Sistema Universitario e della Ricerca [Research and University System Assessment Agency])


- Reviewer for the following scientific journals:

European Heart Journal

American Journal of Cardiology

Journal of Thrombosis and Haemostasis


Teaching Activities

Since 1989, Prof. Sanguigni has taught the following courses at the Università “Tor Vergata” Faculty of Medicine:
- Internal Medicine courses as part of the Medicine and Surgery Degree Program
- Courses at the School of Specialization in Cardiology and the School of Specialization in Internal Medicine
- Courses on Emergency Medicine and Internal Medicine as part of the Accelerated Degree Program in Nursing Sciences, Midwifery, and Podology



Scientific Activity

Prof. Sanguigni’s scientific activity includes numerous presentations at national and international conferences and publications in the leading international scientific journals on topics related to cardiovascular diseases. 

- He has focused particular attention on the study of pathogenetic mechanisms of atherosclerotic disease and the study of cardiovascular aging through research on the relationships between new mediators of inflammation, markers of oxidative stress, and thrombosis.

- His main areas of research in the past several years belong to three innovative fields: 

1) The first has been dedicated to the in vitro and in vivo study of pleiotropic effects of statins and some antihypertensive drugs, particularly with regard to their anti-inflammatory effect. For the first time in the literature, a clear antioxidant effect unrelated to the cholesterol-lowering effect was demonstrated (Circulation. February 1, 2005; 111 (4):412-9-Citation Index: 100)

2) The second concerned the study of new pathogenetic mechanisms associated with the production of free radicals of oxygen by platelets. For the first time, the pathogenetic role of the gp91 subunit of NADPH oxidase was demonstrated thanks to the discovery of patients with a rare genetic deficiency of NADPH oxidase, which reduced exposure to atherosclerotic disease (Circulation. October 20, 2009; 120 (16):1616-22.).

3) The third innovative and most recent field of research brought into focus for the first time the role of some superfoods in preventing cardiovascular diseases and improving physical performance, with the development of a select mixture of foods with a high polyphenol content, which was also patented (Nutrition Jan 2017; 33: 225/233):